Our Clinical Trials Network (CTN) was formed with the primary objective of facilitating and promoting investigator-initiated, collaborative, multicentre clinical research in emergency medicine (EM) throughout Australia and Aotearoa New Zealand.
The CTN is a College Network. It has a documented executive and management structure, and formal policies and procedures for approving and conducting clinical trials, as well as reporting and disseminating results. A FACEM Executive steers the Network, with administrative support provided by ACEM.
Through collaboration, and the power of a shared track record, the CTN will unite emergency medicine researchers in further raising the profile of ED-based research, increasing the share of competitive funding that it attracts and, most importantly, improving outcomes for our patients by answering those research questions that are most relevant to the quality of their care. The track record developed with each project, will be able to be used by all future endorsed projects.
The Network aims to bring together Australasian researchers with an interest in clinical research to facilitate conducting high quality, multicentre trials. We will be answering research questions that are important to our patients; which are competitive in funding applications.
In time, as emergency medicine research in Australia and Aotearoa New Zealand becomes better recognised and more competitive, we aim to pursue collaboration with international emergency medicine research networks.
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Who can be a member?

The CTN has an open, broad-based membership of FACEMs, trainees, other clinical and allied health professionals (for example, paramedics, nurses, pharmacists, and public health physicians) and non-clinical staff. There is a requirement that members are involved with or interested in EM research. Full membership, which is available to FACEMs, enables individuals to nominate for a position on the Executive.
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What is expected of members?

Members must be willing to:
- receive updates from the Network
- be notified of requests from researchers who might be interested in collaborating
- consider which endorsed multi-centre clinical trials might be appropriate for your site.
Contingent on explicit consent being received from individuals, information regarding specific research interests and expertise may be shared as required amongst the membership.
For example, a researcher may seek to collaborate with a toxicology researcher, a regional ED in Victoria, an epidemiologist or a hospital that has a high caseload of geriatric presentations. If consent is received there is no obligation on members to collaborate when requested, only to be open to an approach.
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Become a member

You can apply to become a member via the form below.
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Network Executive

The CTN has a small Executive to steer the network and report to the College governance structures. The main role of the Executive is to provide critical review of research proposals and, endorse projects that meet relevant guidelines. To learn more about the role of the Executive read the Terms of Reference.
Under its Terms of Reference the Executive comprises 10 FACEM members and one FACEM Trainee member. The Executive Committee following the recent committee spill now consists of:
- Dr Elyssia Bourke, Chair
- Prof Diana Egerton-Warburton, Deputy Chair
- Dr Paul Buntine, FACEM member
- A/Prof Daniel Haustead, FACEM member
- Dr Frances Kinnear, FACEM member
- A /Prof Viet Tran, FACEM member
- Dr Gina Watkins, FACEM member
The Executive will be joined in their meetings by observers from the New Zealand Emergency Medicine Network and Paediatric Research in Emergency Departments International Collaboration (PREDICT).
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How will my details be used?

Your contact and other details will be obtained only for the specified purpose of receiving information and requests that are explicitly associated with the activities of the CTN. Details shall not be further processed in any manner incompatible with that purpose.
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CTN-Endorsed research projects and publications

These projects have been endorsed by the ACEM CTN. Read more about project endorsement..
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Title
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Principal Investigator
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Endorsed
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Implementation Research to Improve Outcomes in Primary Spontaneous Pneumothorax: iIMPROVE PSP Trial
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Professor Diana Egerton-Warburton
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6/2/2026
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ADAPT-ED: Adaptive Trial of Emergency Department Interventions for Back Pain
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Assoc. Professor Gustavo Machado
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20/11/2025
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SMART-ED: a sequential multiple assignment trial in emergency departments testing optimal implementation strategies of back pain guideline
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Assoc. Professor Gustavo Machado
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19/9/2024
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Implementing Best Practice for Peripheral Intravenous Cannula in Australian Emergency Departments: A Stepped-Wedge Cluster Controlled Trial and Health Economic Analysis.
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Professor Diana Egerton-Warburton
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16/11/2023
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PEAChY-M: Pharmacological Emergency management of Agitation in Children and Young people – a randomised controlled trial of intraMuscular medication.
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Dr Elyssia Bourke
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12/08/2021
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Bedside Ultrasound Conducted in Kids with distal upper Limb fractures in the Emergency Department, randomised controlled trial (BUCKLED RCT).
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Dr Peter Snelling
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16/02/2021
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Fibrinogen Early In Severe Trauma studY II (FEISTY II).
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Dr James Winearls
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09/12/2020
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PEAChY-O – Pharmacological Emergency management of Agitation in Children and Young people (Oral Medication)
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Dr Elyssia Bourke
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15/09/2020
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Pragmatic Paediatric Trial of Balanced versus Normal Saline fluid in Sepsis
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Dr Elliot Long
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17/03/2020
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Investigating the ability of algorithms and machine learning to predict emergency department wait times for patients
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Clinical Professor Katie Walker
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24/12/2019
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Clinical Outcomes Measurement in Perioperative Medicine, Anaesthesia & Surgery Study (COMPASS): Development of an Australian perioperative mortality risk prediction model
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Dr Jennifer Reilly
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01/04/2019
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Australasian Resuscitation In Sepsis Evaluation: FLUid or Vasopressors In Emergency Department Sepsis (ARISE FLUIDS)*
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Dr Stephen Macdonald
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07/06/2018
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List of publications:
- Keijzers G, Thom O, Taylor DMcD, Knott JC for the ACEM Clinical Trials Group. Clinical Research Priorities in Emergency Medicine. Emerg Med Australas 2014; 26: 19-27. [Login required]
- Thom O, Keijzers G, Davies S, Taylor DMcD, Knott J, Middleton P. Clinical Research Priorities in Emergency Medicine: Results of a Consensus Meeting and Development of a Weighting Method for Assessment of Clinical Research Priorities. Emerg Med Australas 2014; 26, 28–33. [Login required]
- Taylor DMcD, Fatovich D, Finucci D, Furyk J, Hughes J, Jin S-W, Keijzers G, MacDonald S, Mitenko H, Richardson J, Ting J, Thom O, Ugoni A, Ward M et al. Best-practice Pain Management in the ED: a multi-centre, cluster-randomised, controlled, clinical intervention trial. Emerg Med Australas 2015; 27: 549-557. [Login required]
- Taylor DMcD, Cohen DR, Epstein J, Freeman P, Gosbell AD, Judkins S, Mowatt EJ, O'Reilly GM1, Vinen J. Development of a productive research culture in emergency medicine: Report of the outcomes of a research forum. Emerg Med Australas. 2016; 28(1): 113-8. [Free full text]
- Thom ON, Keijzers G, Taylor DMcD, Fatovich DM, Finucci DP, Furyk J, Jin S, Macdonald SPJ, Mitenko HMA, Richardson JB, Ting JYS, Gibbs CR, Chalkley DR. The TARGET Pain Study – Lessons from a painful marathon. Emerg Med Australas. 2016; 28(5): 603-6. [Login required]
- Furyk J, Lawton L, Ting J, Taylor DMcD for the Australasian College of Emergency Medicine Clinical Trials Group. Perspective: Informed consent in emergency care research: An oxymoron? Emerg Med Australas 2017; 29 (1):110-112. [Login required]
- Walker K, Jiarpakdee J, Loupis A, Tantithamthavorn C, Joe K, Ben-Meir M, Akhlaghi H, Hutton JE, Wang WC, Stephenson M, Blecher GE, Buntine PG, Sweeny A, Turhan B, Australasian College for Emergency Medicine Clinical Trials Network. Emergency medicine patient wait time multivariable prediction models: a multicentre derivation and validation study. Emerg Med J. 2022; 39(5): 386-393. [Login required]
- Keijzers G, Macdonald SPJ, Udy AA, Arendts G, Bailey M, Bellomo R et al. The Australasian Resuscitation In Sepsis Evaluation: Fluids or vasopressors in emergency department sepsis (ARISE FLUIDS), a multi-centre observational study describing current practice in Australia and New Zealand. Emerg Med Australas. 2020; 32(4): 586-598. [Login required]
- Howe BD, Macdonald SPJ, Arendts G, Bellomo R, Burcham J, Delaney A, Egerton-Warburton D, Fatovich D, Fraser JF, Higgins A, Jones P, Keijzers G, Milford E, Udy AA, Williams P, Young P, Peake SL. Australasian Resuscitation In Sepsis Evaluation: FLUid or vasopressors In emergency Department Sepsis (ARISE FLUIDS) trial: study protocol. BMJ Open. 2025; 15(7): e101215. [Free full text]
- Milford EM, Macdonald SPJ, Serpa-Neto A et al. Statistical analysis plan for the Australasian Resuscitation in sepsis evaluation: FLUid or vasopressors in emergency department sepsis (ARISE FLUIDS) trial. Crit Care Resusc. 2025; 27(4): 100157. [Free full text]
- Snelling PJ, Jones P, Bade D, Bindra R, Byrnes J, Davison M, George S, Moore M, Keijzers G, Ware RS; BUCKLED Trial Group. Ultrasonography or Radiography for Suspected Pediatric Distal Forearm Fractures. N Engl J Med. 2023; 388(22): 2049-2057. [Login required]
- Snelling PJ, Keijzers G, Byrnes J, Bade D, George S, Moore M, Jones P, Davison M, Roan R, Ware RS. Bedside Ultrasound Conducted in Kids with distal upper Limb fractures in the Emergency Department (BUCKLED): a protocol for an open-label non-inferiority diagnostic randomised controlled trial. Trials. 2021; 22(1): 282. [Free full text]
- Winearls J, Wullschleger M, Wake E, McQuilten Z, Reade M, Hurn C, Ryan G, Trout M, Walsham J, Holley A, George S, Dyer W, McCullough J, Keijzers G, Fraser J, Presneill J, Campbell D. Fibrinogen Early In Severe Trauma studY (FEISTY): results from an Australian multicentre randomised controlled pilot trial. Crit Care Resusc. 2021; 23(1): 32-46. [Free full text]
- Bourke EM, Kochar A, Shellshear D, Borland ML, Jani S, George S, Tham D, Gordon M, Klein K, Wilson CL, Prakash C, Phillips N, Nieva G, Selman CJ, Lee KJ, Davidson A, Knott JC, Craig SS, Babl FE; on behalf of the PREDICT Research Network. PEAChY-O: Pharmacological Emergency Management of Agitation in Children and Young People: A Randomized Controlled Trial of Oral Medication. Ann Emerg Med. 2025; 86(1): 1-11. [Login required]
- Bourke EM, Borland ML, Kochar A, George S, Shellshear D, Jani S, Perkins K, Tham D, Gordon MS, Klein K, Prakash C, Lee K, Davidson A, Knott JC, Craig S, Babl FE; PREDICT Research Network. Pharmacological emergency management of agitation in children and young people: protocol for a randomised controlled trial of oral medication (PEAChY-O). BMJ Open. 2023; 13(3): e067433. [Free full text]
- Bourke EM, Borland ML, Kochar A, George S, Shellshear D, Jani S, Perkins K, Tham D, Gordon MS, Klein K, Prakash C, Lee K, Davidson A, Knott JC, Craig S, Babl FE; PREDICT Research Network. Pharmacological Emergency management of Agitation in Children and Young people: protocol for a randomised controlled trial of intraMuscular medication (PEAChY-M). BMJ Open. 2023; 13(3): e067436. [Free full text]
- Egerton-Warburton D, Kuhn L, Enticott J, Yang SN-Y, Buntine P, Callander E, Cullen L, Fatovich D et al. Implementing best practice for peripheral intravenous cannula use in Australian emergency departments: a stepped-wedge cluster-controlled trial and health economic analysis protocol. BMJ Open. 2025; 15(6): e096962. [Free full text]
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CTN Newsletter

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Discussion forum

Network members can access the discussion forum here.
For further information contact:
ACEM Research Coordinator
+61 (3) 9320 0444
[email protected]
